Last update
3/22/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Glutathione (Reduced Form)
500 mg
**
Milk Thistle Extract (Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)
100 mg
**
Alpha Lipoic Acid
50 mg
**
Top Medical Research Studies
9
We explored how silibinin, derived from the milk thistle plant, affects Candida albicans, the yeast that can lead to infections. Our research demonstrated that silibinin treatment significantly increased reactive oxygen species, triggering a cascade of events that caused yeast cell death, or apoptosis. Notably, we observed that mitochondrial calcium overload plays a vital role in this process. While silibinin shows promise for combating yeast infections, our findings highlight the importance of further research to fully understand its potential and mechanisms.
Read More
8
We investigated how silibinin, a compound from milk thistle, impacts yeast infections, specifically targeting Candida albicans. The study revealed that silibinin demonstrates antifungal properties by damaging the fungal plasma membrane and preventing biofilm formation.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
Read More
Most Useful Reviews
8
Various benefits
This product offers delightful benefits as an antioxidant. It has shown anti-aging properties, reduced inflammation, alleviated depression, and may lower the risk of Alzheimer's and Parkinson's diseases. Furthermore, it fights infections and might even be effective in treating viruses!
Read More
7.5
Eased infections
Since I started taking this supplement, my stomach and colon infections have lessened. It’s of good quality and has proved useful for my needs, so I would recommend it based on my personal experience.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We explored how silibinin, derived from the milk thistle plant, affects Candida albicans, the yeast that can lead to infections. Our research demonstrated that silibinin treatment significantly increased reactive oxygen species, triggering a cascade of events that caused yeast cell death, or apoptosis. Notably, we observed that mitochondrial calcium overload plays a vital role in this process. While silibinin shows promise for combating yeast infections, our findings highlight the importance of further research to fully understand its potential and mechanisms.
Read More
8
We investigated how silibinin, a compound from milk thistle, impacts yeast infections, specifically targeting Candida albicans. The study revealed that silibinin demonstrates antifungal properties by damaging the fungal plasma membrane and preventing biofilm formation.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8
Various benefits
This product offers delightful benefits as an antioxidant. It has shown anti-aging properties, reduced inflammation, alleviated depression, and may lower the risk of Alzheimer's and Parkinson's diseases. Furthermore, it fights infections and might even be effective in treating viruses!
Read More
7.5
Eased infections
Since I started taking this supplement, my stomach and colon infections have lessened. It’s of good quality and has proved useful for my needs, so I would recommend it based on my personal experience.
Read More
Frequently Asked Questions
8
We investigated how silibinin, a compound from milk thistle, impacts yeast infections, specifically targeting Candida albicans. The study revealed that silibinin demonstrates antifungal properties by damaging the fungal plasma membrane and preventing biofilm formation.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
After testing various concentrations, we observed significant membrane disruption at doses over 100 µg/mL. This shows that silibinin not only affects the yeast's structure but also hampers its ability to form protective biofilms.
Overall, while promising, more research is needed to fully understand silibinin’s effectiveness as a widespread treatment for yeast infections.
9
We explored how silibinin, derived from the milk thistle plant, affects Candida albicans, the yeast that can lead to infections. Our research demonstrated that silibinin treatment significantly increased reactive oxygen species, triggering a cascade of events that caused yeast cell death, or apoptosis. Notably, we observed that mitochondrial calcium overload plays a vital role in this process. While silibinin shows promise for combating yeast infections, our findings highlight the importance of further research to fully understand its potential and mechanisms.
References
- Yun DG, Lee DG. Assessment of silibinin as a potential antifungal agent and investigation of its mechanism of action. IUBMB Life. 2017;69:631. 10.1002/iub.1647
- Yun DG, Lee DG. Silibinin triggers yeast apoptosis related to mitochondrial Ca influx in Candida albicans. Int J Biochem Cell Biol. 2016;80:1. 10.1016/j.biocel.2016.09.008
Data last updated:
